MetaPocket 2.0 is a meta server to identify ligand binding sites on protein surface! metaPocket is a consensus method, in which the predicted binding sites from eight methods: LIGSITEcs, PASS, Q-SiteFinder, SURFNET, Fpocket, GHECOM, ConCavity and POCASA are combined together to improve the prediction success rate.
The first version of metapocket (metapocket 1.0, URL: http://metapocket.eml.org ) was developed at Heidelberg Insititute for Theoretical Studies (link) (formerly EML Research gGmbH). Then it is continuely developed at Techincal University of Dresden and Zhejiang University jointly.
MetaPocket 2.0 is both maintained at two web-sites:
About how to use this server, please refer to our usage and helps.
New features of metaPocket 2.0 are shown in the feature page.
The algorithem of metaPocket 2.0 and the element predictors are shown in the algorithm page.
Funding from Klaus Tschira Foundation, MOST China (grant no: 2008DFA11320) and EU 7th Framework Marie Curie Actions IRSES project (grant no: 247097) is kindly acknowledged!
Comments and bugs please contact: Dr. Bingding Huang, E-mail: bhuang@biotec.tu-dresden.de, and Zengming Zhang, Email: zmzhang@mail.systemsbiozju.org
MetaPocket2.0 is free for academic users. If you desire to use metaPocket2.0 at your site for profit-making or commercial purposes, please contact us first.
How to cite metaPocket 2.0:
Bingding Huang (2009), metaPocket: a meta approach to improve protein ligand binding site prediction , Omics, 13(4), 325-330
If this server is useful for your work, please cite:Zengming Zhang, Yu Li, Biaoyang Lin, Michael Schroeder and Bingding Huang (2011), Identification of cavities on protein surface using multiple computational approaches for drug binding site prediction. Bioinformatics, 27 (15): 2083-2088. link
Bingding Huang (2009), metaPocket: a meta approach to improve protein ligand binding site prediction , Omics, 13(4), 325-330 Link, PDF.
Contact us
Bingding Huang, Email: bhuang@biotec.tu-dresden.de
Zengming Zhang, Email: zmzhang@mail.systemsbiozju.org
Report BugsIf you find some bugs of this server, please help us improve metaPocket by reporting bugs to Zengming Zhang, any help from you will be greatly appreciated!
AcknowledgementFunding from Klaus Tschira Foundation, MOST China (grant no: 2008DFA11320) and EU 7th Framework Marie Curie Actions IRSES project (grant no: 247097) is kindly acknowledged!
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